Novel spliced variants of OCT4, OCT4C and OCT4C1, with distinct expression patterns and functions in pluripotent and tumor cell lines.
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DOI: 10.1016/j.ejcb.2017.03.009
Abstract: OCT4 is a major regulator of pluripotency which has several spliced variants and expressed pseudogenes. Here, we are reporting the existence of two additional novel spliced variants of OCT4, OCT4C and OCT4C1, which lack Exon1… read more here.
Keywords: variants oct4; oct4c oct4c1; novel spliced; spliced variants ... See more keywords
A novel spliced variant of the TIN2 shelterin is present in chronic lymphocytic leukemia.
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DOI: 10.1016/j.leukres.2017.05.017
Abstract: The shelterin proteins play important roles in telomere maintenance and genome stability. These proteins have been found to be mutated in many cancers including CLL. Herein, we demonstrate here the presence of a novel spliced… read more here.
Keywords: lymphocytic leukemia; spliced tin2s; tin2s; novel spliced ... See more keywords