Novel structural hybrids of quinoline and thiazole moieties: Synthesis and evaluation of antibacterial and antifungal activities with molecular modeling studies.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.104803
Abstract: One of the best ways to design new biocidal agents is synthesizing hybrid molecules by combining two or more bioactive moieties in a single molecular scaffold. So, new series of quinolines bearing a thiazole moiety… read more here.
Keywords: antibacterial antifungal; structural hybrids; antifungal activities; inhibition growth ... See more keywords
A novel structural resilience index: Definition and applications to frame structures
Sign Up to like & getrecommendations! Published in 2019 at "Mechanics Research Communications"
DOI: 10.1016/j.mechrescom.2019.03.007
Abstract: Abstract Resilience is the ability to undergo disruptive events without suffering complete failure and minimizing undesirable consequences thereof. Many attempts have been done in the recent literature in order to define quantitatively synthetic resilience measures… read more here.
Keywords: structural resilience; number; novel structural; resilience index ... See more keywords
Design optimization and fabrication of a novel structural piezoresistive pressure sensor for micro-pressure measurement
Sign Up to like & getrecommendations! Published in 2018 at "Solid-state Electronics"
DOI: 10.1016/j.sse.2017.09.012
Abstract: Abstract This paper presents a novel structural piezoresistive pressure sensor with a four-beams-bossed-membrane (FBBM) structure that consisted of four short beams and a central mass to measure micro-pressure. The proposed structure can alleviate the contradiction… read more here.
Keywords: micro pressure; structural piezoresistive; novel structural; piezoresistive pressure ... See more keywords
Novel Structural Hybrids on the Base of Benzofuroxans and Furoxans. Mini-Review.
Sign Up to like & getrecommendations! Published in 2017 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026616666160927145822
Abstract: Hybrid drug strategy is based on the combination of two or more pharmacophores into a new chemical entity to improve the properties of the original compounds or to obtain double action of resulting molecule. Hybrid… read more here.
Keywords: structural hybrids; base benzofuroxans; novel structural; furoxans mini ... See more keywords
In Silico Discovery and Optimisation of a Novel Structural Class of Hsp90 C-Terminal Domain Inhibitors
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12070884
Abstract: Hsp90 is a promising target for the development of novel agents for cancer treatment. The N-terminal Hsp90 inhibitors have several therapeutic limitations, the most important of which is the induction of heat shock response, which… read more here.
Keywords: hsp90 ctd; structural class; hsp90; novel structural ... See more keywords