Novel TDP1 Inhibitors: Disubstituted Thiazolidine-2,4-Diones Containing Monoterpene Moieties
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DOI: 10.3390/ijms24043834
Abstract: Tyrosyl-DNA-phosphodiesterase 1 (TDP1) is a promising target for antitumor therapy; the use of TDP1 inhibitors with a topoisomerase 1 poison such as topotecan is a potential combination therapy. In this work, a novel series of… read more here.
Keywords: inhibitors disubstituted; disubstituted thiazolidine; novel tdp1; diones containing ... See more keywords