Novel therapeutics in supportive cancer treatment
Sign Up to like & getrecommendations! Published in 2017 at "memo - Magazine of European Medical Oncology"
DOI: 10.1007/s12254-017-0353-1
Abstract: SummaryWith constantly improving cancer therapies, patient’s quality of life, the management of potential side effects and treatment-related symptoms have also made considerable progress. Chemotherapy-induced nausea and vomiting (CINV) still constitutes a major problem for many patients.… read more here.
Keywords: supportive cancer; novel therapeutics; therapeutics supportive; treatment ... See more keywords
Targeting O-GlcNAcylation to develop novel therapeutics.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular aspects of medicine"
DOI: 10.1016/j.mam.2020.100885
Abstract: O-linked β-D-N-acetylglucosamine (O-GlcNAc) is an abundant post-translational modification (PTM) that modifies the serine or threonine residues of thousands of proteins in the nucleus, cytoplasm and mitochondria. Being a major "nutrient sensor" in cells, the O-GlcNAc… read more here.
Keywords: glcnac; novel therapeutics; targeting glcnacylation; develop novel ... See more keywords
Clinical trials and novel therapeutics in dermatomyositis
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Emerging Drugs"
DOI: 10.1080/14728214.2020.1787985
Abstract: ABSTRACT Introduction Currently, there are no proven drugs that are FDA approved for the treatment of dermatomyositis (DM), even though multiple clinical trials are ongoing to evaluate safety and efficacy of novel therapeutics in DM.… read more here.
Keywords: therapeutics dermatomyositis; trials novel; clinical trials; novel therapeutics ... See more keywords
Perspectives on Access to Novel Therapeutics Through Clinical Trials Among Adolescents and Young Adults with Advanced Cancer: Implications for Patient-Centered Clinical Trials.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of adolescent and young adult oncology"
DOI: 10.1089/jayao.2021.0152
Abstract: Purpose: Adolescents and young adults (AYA) with advanced cancer have unequal access to and enrollment in clinical trials. Many AYA use online platforms to share their treatment experiences. The purpose of this analysis was to… read more here.
Keywords: adolescents young; novel therapeutics; clinical trials; advanced cancer ... See more keywords
Novel Therapeutics in Nonalcoholic Fatty Liver Disease: A Focus on Adult Stem Cells.
Sign Up to like & getrecommendations! Published in 2023 at "Metabolic syndrome and related disorders"
DOI: 10.1089/met.2022.0069
Abstract: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder that is associated with abnormal accumulation of fat in the liver, which can lead to a wide variety of pathological liver defects and… read more here.
Keywords: nonalcoholic fatty; novel therapeutics; fatty liver; disease ... See more keywords
Novel therapeutics for bronchopulmonary dysplasia
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Pediatrics"
DOI: 10.1097/mop.0000000000000613
Abstract: Purpose of review This review provides a concise summary of recent literature pertaining to emerging therapies for bronchopulmonary dysplasia (BPD). To provide context for the presented therapies, a brief overview of recently proposed changes to… read more here.
Keywords: bronchopulmonary dysplasia; novel therapeutics; dysplasia; bpd ... See more keywords
Pancreas adenocarcinoma: novel therapeutics.
Sign Up to like & getrecommendations! Published in 2017 at "Chinese clinical oncology"
DOI: 10.21037/cco.2017.06.14
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is the third highest cause of cancer-related deaths in the US, and is projected to be second only to non-small cell lung cancer (NSCLC) by the 2020s. Current therapies have a… read more here.
Keywords: pancreas adenocarcinoma; novel therapeutics; adenocarcinoma novel; cancer ... See more keywords
Novel Therapeutics for the treatment of Alzheimer's and Parkinson's disorders.
Sign Up to like & getrecommendations! Published in 2020 at "Current pharmaceutical design"
DOI: 10.2174/1381612826666200107161051
Abstract: Neurodegenerative diseases are a leading apprehension in underdeveloped and developed countries. The advancement of medical science is synonymous with an increase in life expectancy, which results in an aging population. Neurodegenerative diseases in the older… read more here.
Keywords: novel therapeutics; therapeutics treatment; parkinson; neurodegenerative diseases ... See more keywords
Discovery of Novel Therapeutics for Muscular Dystrophies using Zebrafish Phenotypic Screens
Sign Up to like & getrecommendations! Published in 2019 at "Journal of neuromuscular diseases"
DOI: 10.3233/jnd-190389
Abstract: The recent availability and development of mutant and transgenic zebrafish strains that model human muscular dystrophies has created new research opportunities for therapeutic development. Not only do these models mimic many pathological aspects of human… read more here.
Keywords: discovery novel; novel therapeutics; development; dystrophies using ... See more keywords
Probiotics: Potential Novel Therapeutics Against Fungal Infections
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2021.793419
Abstract: The global infection rate of fungal diseases is increasing year by year, and it has gradually become one of the most serious infectious diseases threatening human health. However, the side effects of antifungal drugs and… read more here.
Keywords: potential novel; novel therapeutics; therapeutics fungal; infection ... See more keywords
Molecular Targets for Novel Therapeutics in Pediatric Fusion-Positive Non-CNS Solid Tumors
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.747895
Abstract: Chromosomal fusions encoding novel molecular drivers have been identified in several solid tumors, and in recent years the identification of such pathogenetic events in tumor specimens has become clinically actionable. Pediatric sarcomas and other rare… read more here.
Keywords: molecular targets; novel therapeutics; cns; solid tumors ... See more keywords