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Novel 2-Thiouracil-5-Sulfonamide Derivatives: Design, Synthesis, Molecular Docking, and Biological Evaluation as Antioxidants with 15-LOX Inhibition

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Published in 2023 at "Molecules"

DOI: 10.3390/molecules28041925

Abstract: New antioxidant agents are urgently required to combat oxidative stress, which is linked to the emergence of serious diseases. In an effort to discover potent antioxidant agents, a novel series of 2-thiouracil-5-sulfonamides (4–9) were designed… read more here.

Keywords: molecular docking; synthesis; lox inhibition; thiouracil sulfonamide ... See more keywords