Olumacostat glasaretil, a novel topical sebum inhibitor, in the treatment of acne vulgaris: A phase IIa, multicenter, randomized, vehicle‐controlled study
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2016.08.053
Abstract: Background: Olumacostat glasaretil (OG) inhibits acetyl‐coenzyme A carboxylase, the enzyme responsible for the first, rate‐limiting step in de novo fatty acid synthesis. OG inhibited in vitro human sebocyte lipid production and reduced in vivo sebaceous… read more here.
Keywords: treatment; vehicle; olumacostat glasaretil; acne vulgaris ... See more keywords
Novel topical nano-colloidal carrier loaded with cyclosporine: Biological evaluation potentially for psoriasis treatment
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2021.102440
Abstract: Abstract Psoriasis is an autoimmune condition appeared as a skin disease, spotted as dry skin with red and thick plagues, which commonly induce itchiness and extreme uncomfortable feeling to the patient. In any level of… read more here.
Keywords: irritancy; novel topical; cyclosporine; nanoemulsion ... See more keywords
Ferulic acid – A novel topical agent in reducing signs of photoaging
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DOI: 10.1111/dth.15543
Abstract: Continuous production of reactive oxygen species, induced by UV radiation, is one of the main mechanisms contributing to skin photoaging. Therefore, the use of novel superior antioxidants, which ferulic acid belongs to, is an innovative… read more here.
Keywords: topical agent; acid novel; novel topical; agent reducing ... See more keywords
Systemic treatments for melasma: adjuvant therapy with a novel topical agent
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Dermatology"
DOI: 10.1111/ijd.13887
Abstract: References 1 Durdu M, Guran M, Ilkit M. Epidemiological characteristics of Malassezia folliculitis and use of the May-Grunwald-Giemsa stain to diagnose the infection. Diagn Microbiol Infect Dis 2013; 76: 450–457. 2 Lim SL, Lim CS.… read more here.
Keywords: melasma adjuvant; adjuvant therapy; treatments melasma; systemic treatments ... See more keywords
A novel topical therapy for resistant and early peristomal pyoderma gangrenosum
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DOI: 10.1111/iwj.13164
Abstract: Peristomal pyoderma gangrenosum (PPG) is an under‐recognised and difficult condition to treat. We describe a case series using a novel topical combination therapy that promotes wound healing and allows for adhesion of the stoma appliance.… read more here.
Keywords: topical therapy; peristomal pyoderma; pyoderma gangrenosum; therapy ... See more keywords
Clascoterone: A Novel Topical Androgen Receptor Inhibitor for the Treatment of Acne
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DOI: 10.1177/1060028021992053
Abstract: Objective: To review the efficacy and safety of clascoterone 1% cream for the treatment of acne vulgaris in patients 12 years of age and older. Data Sources: A literature search through PubMed, MEDLINE, and ClinicalTrials.gov… read more here.
Keywords: treatment; topical androgen; treatment acne; clascoterone ... See more keywords