A novel topoisomerase 2a inhibitor, cryptotanshinone, suppresses the growth of PC3 cells without apparent cytotoxicity
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DOI: 10.1016/j.taap.2017.07.007
Abstract: ABSTRACT DNA topoisomerase 2, which is ubiquitously expressed in eukaryotic cells, is an essential nuclear enzyme that promotes cell survival by regulating DNA topology and chromatid separation. This enzyme has been validated as a target… read more here.
Keywords: topoisomerase inhibitor; novel topoisomerase; cryptotanshinone; topoisomerase ... See more keywords