Design and synthesis of novel spirooxindole–indenoquinoxaline derivatives as novel tryptophanyl-tRNA synthetase inhibitors
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DOI: 10.1007/s11030-019-10011-2
Abstract: In the current study, we used an integrated approach combining bioinformatics, rational drug design, one-pot synthesis, and biological experiments in vitro for the potential discovery of novel tryptophanyl-tRNA synthetase (TrpRS) inhibitors. Atom economic and diastereoselective… read more here.
Keywords: indenoquinoxaline; tryptophanyl trna; spirooxindole indenoquinoxaline; novel tryptophanyl ... See more keywords