Synthesis and evaluation of novel urea and amide derivatives of 2-amino-4-phenylthiazole as potential antibacterial agents
Sign Up to like & getrecommendations! Published in 2017 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-017-1910-1
Abstract: Two series of novel urea- and amide-functionalized 2,4-disubstituted thiazole derivatives were efficiently synthesized and characterized by 1H nuclear magnetic resonance, 13C nuclear magnetic resonance spectroscopy and high-resolution mass spectrometry. The target compounds were evaluated for… read more here.
Keywords: amide derivatives; novel urea; antibacterial activity; activity ... See more keywords
Novel urea derivative-loaded PLGA nanoparticles to inhibit caries-associated Streptococcus mutans
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DOI: 10.1039/d1ra09314b
Abstract: Caries is the most common chronic infectious disease in the human oral cavity and the existing anti-caries agents may lead to drug resistance and microecological imbalance. A novel urea derivative, 1,3-bis[3,5-bis(trifluoromethyl)phenyl]urea, has a potentially prominent… read more here.
Keywords: loaded plga; urea derivative; novel urea; streptococcus mutans ... See more keywords