Abstract B023: Inhibition of RAS signaling and tumorigenesis through targeting novel vulnerabilities
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Cancer Research"
DOI: 10.1158/1557-3125.ras23-b023
Abstract: RAS GTPases are important mediators of oncogenesis with nearly 30% of human tumors harboring mutant RAS proteins. However, pharmacological inhibition of RAS has proven challenging. We have employed Monobody technology to discover novel vulnerabilities in… read more here.
Keywords: signaling tumorigenesis; novel vulnerabilities; ras signaling; inhibition ras ... See more keywords