Coupling riboflavin de novo biosynthesis and cytochrome expression for improving extracellular electron transfer efficiency in Shewanella oneidensis
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28172
Abstract: Shewanella oneidensis MR‐1, as a model exoelectrogen with divergent extracellular electron transfer (EET) pathways, has been widely used in microbial fuel cells (MFCs). The electron transfer rate is largely determined by riboflavin (RF) and c‐type… read more here.
Keywords: novo biosynthesis; biosynthesis; expression; electron transfer ... See more keywords
De Novo Biosynthesis of Polydatin in Saccharomyces cerevisiae.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c01557
Abstract: Polydatin, with better structural stability and biological activities than resveratrol, is mainly extracted from the traditional Chinese medicinal plant Polygonum cuspidatum. In this study, based on the transcriptome analysis of P. cuspidatum, we identified the… read more here.
Keywords: biosynthesis; saccharomyces cerevisiae; novo biosynthesis; polydatin saccharomyces ... See more keywords
De novo Biosynthesis of Salvianolic Acid B in Saccharomyces cerevisiae Engineered with the Rosmarinic Acid Biosynthetic Pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c06329
Abstract: Salvianolic acid B (SAB), also named lithospermic acid B, belongs to a class of water-soluble phenolic acids, originating from plants such as Salvia miltiorrhiza. SAB exhibits a variety of biological activities and has been clinically… read more here.
Keywords: sab; novo biosynthesis; biosynthetic pathway; salvianolic acid ... See more keywords
De Novo Biosynthesis of Methyl Cinnamate in Engineered Escherichia coli.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c02638
Abstract: Methyl cinnamate with a fruity balsamic odor is an important fragrance ingredient in perfumes and cosmetics. Chemical processes are currently the only means of producing methyl cinnamate. But consumers prefer natural flavors. Therefore, it is… read more here.
Keywords: novo biosynthesis; methyl cinnamate; escherichia coli; engineered escherichia ... See more keywords
Perspective on Biotransformation and De Novo Biosynthesis of Licorice Constituents.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.7b04470
Abstract: Licorice, an important herbal medicine, is derived from the dried roots and rhizomes of Glycyrrhiza genus plants. It has been widely used in food, pharmaceutical, tobacco, and cosmetics industries with high economic value. However, overexploitation… read more here.
Keywords: novo biosynthesis; biotransformation novo; perspective biotransformation; biotransformation ... See more keywords
De Novo Biosynthesis of the Anticancer Compound Euphol in Saccharomyces cerevisiae.
Sign Up to like & getrecommendations! Published in 2021 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.1c00257
Abstract: Euphol is a euphane-type tetracyclic triterpene which is primarily found in the Euphorbia genus. Euphol has been renowned because of its great potential as a promising anticancer drug. Surprisingly, despite its diverse antitumor effects, the… read more here.
Keywords: euphol; saccharomyces cerevisiae; biosynthesis anticancer; novo biosynthesis ... See more keywords
De Novo Biosynthesis of D-p-Hydroxyphenylglycine by a Designed Cofactor Self-Sufficient Route and Co-culture Strategy.
Sign Up to like & getrecommendations! Published in 2022 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.2c00007
Abstract: d-p-Hydroxyphenylglycine (D-HPG) is an important intermediate for the synthesis of β-lactam antibiotics with an annual market demand of thousands of tons. Currently, the main production processes are via chemical approaches. Although enzymatic conversion has been… read more here.
Keywords: novo biosynthesis; hydroxyphenylglycine; cofactor self; route ... See more keywords
De novo biosynthesis of (S)- and (R)-phenylethanediol in yeast via artificial enzyme cascades.
Sign Up to like & getrecommendations! Published in 2019 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.9b00123
Abstract: Due to the oil depletion and global climate change, sustainable manufacturing of fine chemicals from renewable feedstocks has gained an increasing attention in the scientific community. In the present study, we attempted to engineer Saccharomyces… read more here.
Keywords: enzyme cascades; novo biosynthesis; artificial enzyme; styrene ... See more keywords
De novo biosynthesis of bioactive isoflavonoids by engineered yeast cell factories.
Sign Up to like & getrecommendations! Published in 2021 at "Nature communications"
DOI: 10.1038/s41467-021-26361-1
Abstract: Isoflavonoids comprise a class of plant natural products with great nutraceutical, pharmaceutical and agricultural significance. Their low abundance in nature and structural complexity however hampers access to these phytochemicals through traditional crop-based manufacturing or chemical… read more here.
Keywords: biosynthesis; cell factories; novo biosynthesis; factories novo ... See more keywords
A highly selective 2''-O-glycosyltransferase from Ziziphus jujuba and De novo biosynthesis of isovitexin 2''-O-glucoside.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d1cc06949g
Abstract: A novel and efficient 2''-O-glycosyltransferase ZjOGT38 was identified from Ziziphus jujuba. It could regio-selectively glycosylate 2-hydroxyflavanone C-glycosides. ZjOGT38 allowed de novo biosynthesis of isovitexin 2''-O-glucoside in E. coli. read more here.
Keywords: novo biosynthesis; isovitexin glucoside; glycosyltransferase; biosynthesis isovitexin ... See more keywords
De novo biosynthesis and whole-cell catalytic production of paracetamol on a gram scale in Escherichia coli
Sign Up to like & getrecommendations! Published in 2021 at "Green Chemistry"
DOI: 10.1039/d1gc02591k
Abstract: We constructed the de novo biosynthesis and whole-cell biocatalysis pathways for the famous drug paracetamol or its analogues. This study provides a promising, sustainable, efficient alternative to the traditional chemical manufacturing methods. read more here.
Keywords: novo biosynthesis; paracetamol; whole cell; biosynthesis whole ... See more keywords