Increased de novo ceramide synthesis and accumulation in failing myocardium.
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DOI: 10.1172/jci.insight.96203
Abstract: Abnormal lipid metabolism may contribute to myocardial injury and remodeling. To determine whether accumulation of very long-chain ceramides occurs in human failing myocardium, we analyzed myocardial tissue and serum from patients with severe heart failure… read more here.
Keywords: novo ceramide; accumulation; ceramide synthesis; failing myocardium ... See more keywords