Enhancement of Pharmaceutical Urate Oxidase Thermostability by Rational Design of De Novo Disulfide Bridge
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DOI: 10.30498/ijb.2020.2662
Abstract: Background and Purpose: As a therapeutic enzyme, urate oxidase is utilized in the reduction of uric acid in various conditions such as gout or tumor syndrome lysis. However, even bearing kinetical advantage over other counterparts,… read more here.
Keywords: novo disulfide; rational design; oxidase; disulfide bridge ... See more keywords