Mid-Term Outcomes After Treatment for Antibody-Mediated Rejection by De Novo Donor-Specific HLA Antibody in Renal Transplant Recipients: Does Early Treatment Lead to Better Outcomes?
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DOI: 10.1016/j.transproceed.2020.06.022
Abstract: BACKGROUND De novo donor-specific HLA antibody (DSA) and antibody-mediated rejection (ABMR) are strongly associated with late allograft loss in renal transplant recipients. However, the impact of therapeutic intervention with the current treatment options for ABMR… read more here.
Keywords: abmr free; treatment; antibody; group ... See more keywords
Complement (C1q) Binding De Novo Donor-Specific Antibodies and Cardiac-Allograft Vasculopathy in Pediatric Heart Transplant Recipients
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DOI: 10.1097/tp.0000000000001944
Abstract: Background We hypothesized C1q binding de novo donor-specific antibody (DSA) after heart transplant (HT) is a higher risk for development of coronary artery vasculopathy (CAV) in children. Methods A retrospective analysis of 127 pediatric HT… read more here.
Keywords: c1q binding; heart; binding novo; dsa ... See more keywords
Protocol Biopsies in Patients With Subclinical De Novo Donor-specific Antibodies After Kidney Transplantation: A Multicentric Study.
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DOI: 10.1097/tp.0000000000003055
Abstract: BACKGROUND De novo donor-specific antibodies (DSAs) are associated with antibody-mediated rejection (AMR) and allograft loss. Whether monitoring of de novo DSA (dnDSA) paired with systematic kidney biopsy should become routine remains to be established. METHODS… read more here.
Keywords: multicentric study; kidney transplantation; specific antibodies; transplantation ... See more keywords
Belatacept Treatment of Recurrent Late-onset T Cell–mediated Rejection/Antibody-mediated Rejection With De Novo Donor-specific Antibodies in a Liver Transplant Patient
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DOI: 10.1097/txd.0000000000001076
Abstract: Background. T cell–mediated rejection that appears and persists late after transplantation is often associated with development of de novo donor-specific antibodies. Treatment of this condition often presents a conundrum because of the uncertainty regarding the… read more here.
Keywords: donor specific; mediated rejection; cell mediated; treatment ... See more keywords
Utility of Protocol Pancreas Biopsies for De Novo Donor-specific Antibodies
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DOI: 10.1097/txd.0000000000001287
Abstract: Copyright © 2022 The Author(s). Transplantation Direct. Published by Wolters Kluwer Health, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is… read more here.
Keywords: biopsies novo; utility protocol; pancreas biopsies; donor specific ... See more keywords
Early clearance vs persistence of de novo donor‐specific antibodies following lung transplantation
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DOI: 10.1111/ctr.13028
Abstract: The natural history of de novo donor‐specific antibodies (dnDSA) after lung transplantation is not well‐described. We sought to determine the incidence and risk factors associated with dnDSA and compare outcomes between recipients with transient (or… read more here.
Keywords: lung transplantation; transplantation; specific antibodies; novo donor ... See more keywords
Screening strategy for de novo donor‐specific HLA antibodies beyond the first year after kidney transplantation: Personalized or “one size fits all”?
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DOI: 10.1111/ctr.14170
Abstract: Screening for de novo donor‐specific HLA antibodies (DSAs) after kidney transplantation is widely recommended. The aim of this single‐center, cross‐sectional study was to investigate the frequency of therapeutic interventions triggered by de novo DSA screening.… read more here.
Keywords: kidney transplantation; specific hla; transplantation; novo donor ... See more keywords
Impact of de novo donor‐specific HLA antibodies on pediatric kidney transplant prognosis in patients with acute declined or stable allograft function
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DOI: 10.1111/petr.14221
Abstract: This retrospective multicenter long‐term cohort study investigates de novo donor‐specific HLA antibodies (dnDSA) impact on allograft survival in pediatric kidney transplantation (KTx), depending on allograft function at dnDSA detection. read more here.
Keywords: allograft; specific hla; donor specific; pediatric kidney ... See more keywords
Development of de novo donor‐specific antibodies in renal transplant recipients with BK viremia managed with immunosuppression reduction
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DOI: 10.1111/tid.13993
Abstract: Reduction of immunosuppression (IS) upon detection of Polyomavirus (BK) viremia is widely used to prevent BK virus nephropathy. This retrospective case‐control study assesses the frequency of de novo donor‐specific antibodies (dnDSA) in renal transplant recipients… read more here.
Keywords: donor specific; specific antibodies; renal transplant; transplant recipients ... See more keywords