HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis.
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DOI: 10.1016/j.ccell.2018.08.018
Abstract: Aberrant expression of HOXA9 is a prominent feature of acute leukemia driven by diverse oncogenes. Here we show that HOXA9 overexpression in myeloid and B progenitor cells leads to significant enhancer reorganizations with prominent emergence… read more here.
Keywords: novo enhancers; leukemogenesis; hoxa9 reprograms; hoxa9 ... See more keywords