A Human‐Specific De Novo Gene Promotes Cortical Expansion and Folding
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DOI: 10.1002/advs.202204140
Abstract: Newly originated de novo genes have been linked to the formation and function of the human brain. However, how a specific gene originates from ancestral noncoding DNAs and becomes involved in the preexisting network for… read more here.
Keywords: gene; gene promotes; specific novo; human specific ... See more keywords
De Novo Gene Birth, Horizontal Gene Transfer, and Gene Duplication as Sources of New Gene Families Associated with the Origin of Symbiosis in Amanita
Sign Up to like & getrecommendations! Published in 2020 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evaa193
Abstract: Abstract By introducing novel capacities and functions, new genes and gene families may play a crucial role in ecological transitions. Mechanisms generating new gene families include de novo gene birth, horizontal gene transfer, and neofunctionalization… read more here.
Keywords: gene families; novo gene; gene birth; symbiosis ... See more keywords
Neutral Models of De Novo Gene Emergence Suggest that Gene Evolution has a Preferred Trajectory
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DOI: 10.1093/molbev/msad079
Abstract: New protein coding genes can emerge from genomic regions that previously did not contain any genes, via a process called de novo gene emergence. To synthesize a protein, DNA must be transcribed as well as… read more here.
Keywords: neutral models; gene emergence; emergence; gene ... See more keywords
A Molecular Portrait of De Novo Genes in Yeasts
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DOI: 10.1093/molbev/msx315
Abstract: &NA; New genes, with novel protein functions, can evolve “from scratch” out of intergenic sequences. These de novo genes can integrate the cell's genetic network and drive important phenotypic innovations. Therefore, identifying de novo genes… read more here.
Keywords: novo genes; yeasts molecular; biology; novo gene ... See more keywords
De novo gene birth
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DOI: 10.1371/journal.pgen.1008160
Abstract: De novo gene birth is the process by which new genes evolve from DNA sequences that were ancestrally non-genic. De novo genes represent a subset of novel genes, and may be proteincoding or instead act… read more here.
Keywords: gene birth; gene; novo gene;
Differences Between the Raw Material and the Products of de Novo Gene Birth Can Result from Mutational Biases.
Sign Up to like & getrecommendations! Published in 2019 at "Genetics"
DOI: 10.1534/genetics.119.302187
Abstract: Proteins are among the most important constituents of biological systems. Because all protein-coding genes have a noncoding ancestral form, the properties of noncoding sequences and how they shape the birth of novel proteins may influence… read more here.
Keywords: raw material; novo gene; gene birth; birth ... See more keywords