From De Novo to “De Nono”: The Majority of Novel Protein-Coding Genes Identified with Phylostratigraphy Are Old Genes or Recent Duplicates
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DOI: 10.1093/gbe/evy231
Abstract: Abstract The evolution of novel protein-coding genes from noncoding regions of the genome is one of the most compelling pieces of evidence for genetic innovations in nature. One popular approach to identify de novo genes… read more here.
Keywords: novel protein; novo genes; phylostratigraphy; protein coding ... See more keywords
A Molecular Portrait of De Novo Genes in Yeasts
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DOI: 10.1093/molbev/msx315
Abstract: &NA; New genes, with novel protein functions, can evolve “from scratch” out of intergenic sequences. These de novo genes can integrate the cell's genetic network and drive important phenotypic innovations. Therefore, identifying de novo genes… read more here.
Keywords: novo genes; yeasts molecular; biology; novo gene ... See more keywords
Tracing the De Novo Origin of Protein-Coding Genes in Yeast
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DOI: 10.1128/mbio.01024-18
Abstract: ABSTRACT De novo genes are very important for evolutionary innovation. However, how these genes originate and spread remains largely unknown. To better understand this, we rigorously searched for de novo genes in Saccharomyces cerevisiae S288C… read more here.
Keywords: spread fixation; birth; novo genes; novo ... See more keywords