Articles with "novo initiation" as a keyword



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An induced-fit de novo initiation mechanism suggested by a pestivirus RNA-dependent RNA polymerase

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Published in 2021 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkab666

Abstract: Abstract Viral RNA-dependent RNA polymerases (RdRPs) play central roles in the genome replication and transcription processes of RNA viruses. RdRPs initiate RNA synthesis either in primer-dependent or de novo mechanism, with the latter often assisted… read more here.

Keywords: initiation; rna dependent; rna; dependent rna ... See more keywords