Sec translocon has an insertase-like function in addition to polypeptide conduction through the channel
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DOI: 10.12688/f1000research.21065.1
Abstract: The Sec translocon provides a polypeptide-conducting channel, which is insulated from the hydrophobic lipidic environment of the membrane, for translocation of hydrophilic passenger polypeptides. Its lateral gate allows a downstream hydrophobic segment (stop-transfer sequence) to… read more here.
Keywords: novo insertion; channel; function; translocon ... See more keywords