De novo metastatic breast cancer in patients with a small locoregional tumour (T1-T2/N0): Characteristics and prognosis.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of cancer"
DOI: 10.1016/j.ejca.2021.09.021
Abstract: INTRODUCTION The estimated rate of de novo metastatic breast cancer (dnMBC) at the time of diagnosis is between 5 to 12%. International guidelines recommend metastatic work-up (MWU) only in women with advanced breast cancer. The… read more here.
Keywords: prognosis; novo metastatic; breast cancer; dnmbc ... See more keywords
Association of SPOP Mutations with Outcomes in Men with De Novo Metastatic Castration-sensitive Prostate Cancer.
Sign Up to like & getrecommendations! Published in 2020 at "European urology"
DOI: 10.1016/j.eururo.2020.06.033
Abstract: Recently, mutations in speckle-type pox virus and zinc finger protein (SPOP) gene (mutant SPOP [mtSPOP]) have been associated with improved outcomes to abiraterone in the castration-resistant setting. We hypothesized that mtSPOP would be associated with… read more here.
Keywords: men novo; castration sensitive; novo metastatic; metastatic castration ... See more keywords
Revision of CHAARTED and LATITUDE criteria among Japanese de novo metastatic prostate cancer patients
Sign Up to like & getrecommendations! Published in 2021 at "Prostate International"
DOI: 10.1016/j.prnil.2021.06.001
Abstract: Abstract Background To identify the real high-risk group among Japanese de novo metastatic prostate cancer patients who fit CHAARTED or LATITUDE criteria. Methods We retrospectively studied patients who fitted CHAARTED (292 patients) and LATITUDE (294… read more here.
Keywords: metastatic prostate; novo metastatic; chaarted latitude; among japanese ... See more keywords
Effects of locoregional radiotherapy in de novo metastatic nasopharyngeal carcinoma: A real-world study
Sign Up to like & getrecommendations! Published in 2021 at "Translational Oncology"
DOI: 10.1016/j.tranon.2021.101187
Abstract: Highlights • Locoregional radiotherapy can prolong OS for patients with de novo metastatic nasopharyngeal carcinoma.• Nasopharyngeal carcinoma patients with oligometastic disease can benefit from locoregional radiotherapy rather than polymetastatic disease. read more here.
Keywords: metastatic nasopharyngeal; nasopharyngeal carcinoma; locoregional radiotherapy; novo metastatic ... See more keywords
Changes in survival in de novo metastatic cancer in an era of new medicines.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the National Cancer Institute"
DOI: 10.1093/jnci/djad020
Abstract: BACKGROUND Over the past decades, the therapeutic landscape has markedly changed for patients with metastatic solid cancer, yet few studies have evaluated its effect on population-based survival. The objective of this study was to evaluate… read more here.
Keywords: year survival; novo metastatic; disease; metastatic cancer ... See more keywords
A Novel Staging System for De Novo Metastatic Breast Cancer Refines Prognostic Estimates
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Surgery"
DOI: 10.1097/sla.0000000000004231
Abstract: Objective: We aim to identify prognostic groups within a de novo metastatic cohort, incorporating both anatomic and biologic factors. Background: Staging for breast cancer now includes anatomic and biologic factors, although the guidelines for stage… read more here.
Keywords: metastatic breast; cancer; breast cancer; stage ... See more keywords
Controversies in Oncology: Surgery of the primary tumour in patients presenting with de novo metastatic breast cancer: to do or not to do?
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DOI: 10.1136/esmoopen-2018-000324
Abstract: Approximately 5%–10% of patients with newly diagnosed breast cancer present with distant metastasis (ie, de novo metastatic disease).1 The appropriate clinical management of patients with de novo metastatic breast cancer is still very controversial; specifically,… read more here.
Keywords: breast; novo metastatic; breast cancer; metastatic breast ... See more keywords
Identifying optimal candidates for local treatment of the primary tumor among patients with de novo metastatic nasopharyngeal carcinoma: a retrospective cohort study based on Epstein–Barr virus DNA level and tumor response to palliative chemotherapy
Sign Up to like & getrecommendations! Published in 2019 at "BMC Cancer"
DOI: 10.1186/s12885-019-5281-5
Abstract: BackgroundTo evaluate the clinical outcome in patients with de novo metastatic nasopharyngeal carcinoma (NPC) treated or not treated with locoregional radiotherapy (LRRT) based on plasma Epstein–Barr virus (EBV) DNA level and tumor response after palliative… read more here.
Keywords: response; dna level; novo metastatic; tumor response ... See more keywords
The prevalence of common KRAS variants and associated outcomes in patients with metastatic colorectal cancer (mCRC).
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2022.40.4_suppl.173
Abstract: 173 Background: KRAS is the most common driver oncogene in mCRC. Comprehensive analysis of KRAS variants prevalence and the relationship between variants and outcomes are lacking. Herein, we aimed to examine the impact of KRAS… read more here.
Keywords: outcomes patients; novo metastatic; kras variants; prevalence ... See more keywords