Constitutional mosaicism of a de novo TP53 mutation in a patient with bilateral choroid plexus carcinoma.
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DOI: 10.1016/j.cancergen.2017.07.001
Abstract: Choroid plexus tumors (CPT) constitute 2%-5% of all pediatric brain tumors and include high grade choroid plexus carcinoma (CPC). About 40% of CPC patients harbor germline TP53 mutations, associated with diminished survival rates. However, the… read more here.
Keywords: choroid plexus; tp53 mutation; mosaicism; novo tp53 ... See more keywords