Abstract 2575: Mechanoactivation of NOX2-generated ROS elicits persistent TRPM8 Ca2+signals that are inhibited by oncogenic KRas
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DOI: 10.1158/1538-7445.am2020-2575
Abstract: Changes in the mechanical microenvironment and mechanical signals are observed during tumor progression, malignant transformation, and metastasis. In this context, understanding the molecular details of mechanotransduction signaling may provide unique therapeutic targets. Here we report… read more here.
Keywords: nox2 generated; oncogenic kras; mechanoactivation nox2; cancer ... See more keywords