High nuclear NADPH oxidase 4 expression levels are correlated with cancer development and poor prognosis in hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2019 at "Pathology"
DOI: 10.1016/j.pathol.2019.05.004
Abstract: NADPH oxidase (NOX) is a key source of reactive oxygen species (ROS). This study aimed to verify NOX2 and NOX4 expression levels in hepatocellular carcinoma (HCC). A total of 134 matched pairs of HCC cells… read more here.
Keywords: hcc; nox2 nox4; expression; expression levels ... See more keywords
Differential effects of NOX2 and NOX4 inhibition after rodent spinal cord injury
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DOI: 10.1371/journal.pone.0281045
Abstract: Reactive oxygen species (ROS) are a contributing factor to impaired function and pathology after spinal cord injury (SCI). The NADPH oxidase (NOX) enzyme is a key source of ROS; there are several NOX family members,… read more here.
Keywords: cord injury; inhibition; nox2 nox4; spinal cord ... See more keywords
Calpain Regulates Reactive Oxygen Species Production during Capacitation through the Activation of NOX2 and NOX4
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24043980
Abstract: Capacitation is a series of physiological, biochemical, and metabolic changes experienced by mammalian spermatozoa. These changes enable them to fertilize eggs. The capacitation prepares the spermatozoa to undergo the acrosomal reaction and hyperactivated motility. Several… read more here.
Keywords: reactive oxygen; capacitation; production; nox2 nox4 ... See more keywords
Effect of Quercetin on the Expression of NOXs and P-Smad3C in TGF-Β-Activated Hepatic Stellate Cell Line LX-2
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DOI: 10.5812/hepatmon.116875
Abstract: Background: Hepatic stellate cells (HSCs) play a primary role in liver fibrogenesis. NOXs are the main origin of reactive oxygen species (ROS) in the liver. Among them, NOX1, NOX2, and NOX4 are expressed more in… read more here.
Keywords: cell line; nox2 nox4; expression; quercetin ... See more keywords