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   Articles with "nox2 ros" as a keyword



Hyperglycemia regulates cardiac K+ channels via O-GlcNAc-CaMKII and NOX2-ROS-PKC pathways

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recommendations! Published in 2020 at "Basic Research in Cardiology"

DOI: 10.1007/s00395-020-00834-8

Abstract: Chronic hyperglycemia and diabetes lead to impaired cardiac repolarization, K+ channel remodeling and increased arrhythmia risk. However, the exact signaling mechanism by which diabetic hyperglycemia regulates cardiac K+ channels remains elusive. Here, we show that… read more here.

Keywords: nox2 ros; hyperglycemia regulates; camkii; hyperglycemia ... See more keywords

Mechanism of miR-320 in Regulating Biological Characteristics of Ischemic Cerebral Neuron by Mediating Nox2/ROS Pathway

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recommendations! Published in 2019 at "Journal of Molecular Neuroscience"

DOI: 10.1007/s12031-019-01434-5

Abstract: This study aimed to explore the mechanism of miR-320 in regulating biological characteristics of ischemic cerebral neuron by mediating Nox2/ROS pathway. Primary neurons were cultured and grouped: normal group (normal primary neurons), negative control (NC)… read more here.

Keywords: nox2 ros; primary neurons; group; ischemic cerebral ... See more keywords

Loss of Scribble confers cisplatin resistance during NSCLC chemotherapy via Nox2/ROS and Nrf2/PD-L1 signaling

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recommendations! Published in 2019 at "EBioMedicine"

DOI: 10.1016/j.ebiom.2019.08.057

Abstract: Background Cisplatin resistance remains a major clinical obstacle to the successful treatment of non-small cell lung cancer (NSCLC). Scribble contributes to ROS-induced inflammation and cisplatin-elevated toxic reactive oxygen species (ROS) promotes cell death. However, it… read more here.

Keywords: chemotherapy; nox2 ros; cisplatin; ros nrf2 ... See more keywords

Group A Streptococcus Induces LAPosomes via SLO/β1 Integrin/NOX2/ROS Pathway in Endothelial Cells That Are Ineffective in Bacterial Killing and Suppress Xenophagy

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recommendations! Published in 2019 at "mBio"

DOI: 10.1128/mbio.02148-19

Abstract: Our previous reports showed that the LC3-associated GAS-containing single membrane vacuoles are inefficient for bacterial clearance in endothelial cells, which may result in bacteremia. However, the characteristics and the induction mechanisms of these LC3-positive vacuoles… read more here.

Keywords: gas; nox2 ros; membrane; endothelial cells ... See more keywords

Honey-fried licorice decoction ameliorates atrial fibrillation susceptibility by inhibiting the NOX2–ROS–TGF-β1 pathway

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recommendations! Published in 2025 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2025.1595111

Abstract: Objective Honey-fried licorice decoction (HFLD), a well-established traditional Chinese medicine, is widely used to treat atrial fibrillation (AF) in China. However, the specific cardioprotective mechanisms of HFLD in treating AF remain unclear. This study aimed… read more here.

Keywords: susceptibility; fried licorice; hfld; nox2 ros ... See more keywords