Deletion of Nox4 enhances remyelination following cuprizone‐induced demyelination by increasing phagocytic capacity of microglia and macrophages in mice
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24292
Abstract: NOX4 is a major reactive oxygen species‐producing enzyme that modulates cell stress responses. We here examined the effect of Nox4 deletion on demyelination–remyelination, the most common pathological change in the brain. We used a model… read more here.
Keywords: deletion; nox4 mice; remyelination; induced demyelination ... See more keywords
NADPH oxidase 4 mediates the protective effects of physical activity against obesity-induced vascular dysfunction.
Sign Up to like & getrecommendations! Published in 2019 at "Cardiovascular research"
DOI: 10.1093/cvr/cvz322
Abstract: AIMS Physical activity is one of the most potent strategies to prevent endothelial dysfunction. Recent evidence suggests vaso-protective properties of H2O2 produced by main endothelial NADPH oxidase isoform 4 (Nox4) in the vasculature. Therefore, we… read more here.
Keywords: dysfunction; nox4 mice; mice; physical activity ... See more keywords