Impact of Mutations on NPAC Structural Dynamics: Mechanistic Insights from MD Simulations
Sign Up to like & getrecommendations! Published in 2019 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.9b00588
Abstract: NPAC is a cytokine-like nuclear factor involved in chromatin modification and regulation of gene expression. In humans, the C-terminal domain of NPAC has the conserved structure of the β-hydroxyacid dehydrogenases (β-HAD) protein superfamily, which forms… read more here.
Keywords: structural dynamics; mutations npac; npac structural; dynamics mechanistic ... See more keywords