CircHIPK3 promotes proliferation and invasion in nasopharyngeal carcinoma by abrogating miR‐4288‐induced ELF3 inhibition
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27041
Abstract: Circular RNAs (circRNAs) are reported to regulate the development and progression of multiple cancers. However, the functions of circRNAs in nasopharyngeal carcinoma (NPC) are unclear. In this study, we identified that circular homeodomain interacting protein… read more here.
Keywords: circhipk3; nasopharyngeal carcinoma; npc; mir 4288 ... See more keywords
EGFR‐rich extracellular vesicles derived from highly metastatic nasopharyngeal carcinoma cells accelerate tumour metastasis through PI3K/AKT pathway‐suppressed ROS
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12003
Abstract: Abstract Nasopharyngeal carcinoma (NPC) is the most common cancer with high metastatic potential that occurs in the epithelial cells of the nasopharynx. Distant metastases are the primary cause for treatment failure and mortality of NPC… read more here.
Keywords: extracellular vesicles; metastatic npc; npc; npc cells ... See more keywords
Niemann-Pick disease type C in the newborn period: a single-center experience
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pediatrics"
DOI: 10.1007/s00431-017-3020-y
Abstract: AbstractNiemann-Pick disease type C (NPC) is a neurovisceral lysosomal storage disorder with a great variation in clinical spectrum and age at presentation. Clinical features of 10 NPC patients who presented in the newborn period between… read more here.
Keywords: npc; period; newborn period; pick disease ... See more keywords
miR‐29c regulates resistance to paclitaxel in nasopharyngeal cancer by targeting ITGB1
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2019.02.012
Abstract: &NA; Paclitaxel (Taxol) is an anticancer taxane drug commonly used in the treatment of nasopharyngeal carcinoma (NPC). However, resistance to paclitaxel is a major difficulty in developing an effective therapy against NPC. MicroRNAs (miRNAs) are… read more here.
Keywords: npc; taxol; resistance; resistance paclitaxel ... See more keywords
The immunologic advantage of recurrent nasopharyngeal carcinoma from the viewpoint of Galectin-9/Tim-3-related changes in the tumour microenvironment
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-10386-y
Abstract: Given salvage treatment for recurrent nasopharyngeal carcinoma (NPC) remains a clinical dilemma, immunotherapy targeting NPC-specific immunosuppression may bring new hope. We analyzed the expression of CD8, CD4, Foxp3 and Tim-3 in lymphocytes, and of Galectin-9… read more here.
Keywords: npc; recurrent npc; expression; recurrent ... See more keywords
miR-26a-5p suppresses nasopharyngeal carcinoma progression by inhibiting PTGS2 expression
Sign Up to like & getrecommendations! Published in 2022 at "Cell Cycle"
DOI: 10.1080/15384101.2022.2030168
Abstract: ABSTRACT Nasopharyngeal carcinoma (NPC) has a low five-year survival rate, and its pathogenesis remains unclear. There is an urgent need to improve our understanding of the genetic regulation of NPC tumorigenesis and development. The role… read more here.
Keywords: nasopharyngeal carcinoma; ptgs2 expression; expression; npc ... See more keywords
TurboID Identification of Evolutionarily Divergent Components of the Nuclear Pore Complex in the Malaria Model Plasmodium berghei
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.01815-22
Abstract: The nuclear pore complex (NPC) is a platform for constant evolution and has been used to study the evolutionary patterns of early-branching eukaryotes. The Plasmodium NPC is poorly defined due to its evolutionary divergent nature… read more here.
Keywords: nuclear pore; pore complex; plasmodium; npc ... See more keywords
Septin 9 Methylation in Nasopharyngeal Swabs: A Potential Minimally Invasive Biomarker for the Early Detection of Nasopharyngeal Carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Disease Markers"
DOI: 10.1155/2020/7253531
Abstract: Nasopharyngeal carcinoma (NPC) is highly prevalent in Southeast Asia, and an unfavorable outcome is usually attributed to advanced stage NPC. Current methods for the early diagnosis of NPC have limitations in clinical practice. The aim… read more here.
Keywords: methylation; npc; septin; detection nasopharyngeal ... See more keywords
Upregulation of PNCK Promotes Metastasis and Angiogenesis via Activating NF-κB/VEGF Pathway in Nasopharyngeal Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/8541582
Abstract: Background Distant metastasis is the major cause of treatment failure in patients with nasopharyngeal carcinoma (NPC). Thus, the identification of the molecular mechanisms and the development of novel therapeutic strategies are important. Previous studies suggest… read more here.
Keywords: metastasis; nasopharyngeal carcinoma; upregulation pnck; pnck ... See more keywords
Abstract 2500: EBV positive NPC-derived exosomes promote macrophage M2 polarization via activating MST1R and YAP1 signalings
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2500
Abstract: Type III Nasopharyngeal carcinoma (NPC) is characterized by Epstein-Barr virus (EBV) infection and immune infiltration. M2 macrophages in the NPC microenvironment are considered to associate with poorer prognosis and promote disease progression. How the tumor-derived… read more here.
Keywords: macrophage polarization; lmp1 exosomes; npc; polarization ... See more keywords
Establishment of a Zebrafish Xenograft Model for in Vivo Investigation of Nasopharyngeal Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Cell Transplantation"
DOI: 10.1177/09636897221116085
Abstract: Nasopharyngeal carcinoma (NPC) is a unique malignant tumor of the head and neck. Despite higher survival rates by the combination of radiotherapy and chemotherapy, the recurrence or metastasis of NPC still occurs at about 10%.… read more here.
Keywords: nasopharyngeal carcinoma; xenograft model; vivo; npc ... See more keywords