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   Articles with "npc" as a keyword



ANKRD22 Induced by Transcription Factor MAZ Promotes Proliferation and Invasion of Nasopharyngeal Carcinoma

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recommendations! Published in 2025 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.70222

Abstract: Nasopharyngeal carcinoma (NPC) is very common in Southeast China, with the characteristics of high aggression and metastasis. Ankyrin repeat domain‐containing protein 22 (ANKRD22) contributes to tumor growth in different tumors, but its role in NPC… read more here.

Keywords: proliferation invasion; npc; ankrd22; nasopharyngeal carcinoma ... See more keywords

CircHIPK3 promotes proliferation and invasion in nasopharyngeal carcinoma by abrogating miR‐4288‐induced ELF3 inhibition

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recommendations! Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.27041

Abstract: Circular RNAs (circRNAs) are reported to regulate the development and progression of multiple cancers. However, the functions of circRNAs in nasopharyngeal carcinoma (NPC) are unclear. In this study, we identified that circular homeodomain interacting protein… read more here.

Keywords: circhipk3; nasopharyngeal carcinoma; npc; mir 4288 ... See more keywords
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EGFR‐rich extracellular vesicles derived from highly metastatic nasopharyngeal carcinoma cells accelerate tumour metastasis through PI3K/AKT pathway‐suppressed ROS

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recommendations! Published in 2020 at "Journal of Extracellular Vesicles"

DOI: 10.1002/jev2.12003

Abstract: Abstract Nasopharyngeal carcinoma (NPC) is the most common cancer with high metastatic potential that occurs in the epithelial cells of the nasopharynx. Distant metastases are the primary cause for treatment failure and mortality of NPC… read more here.

Keywords: extracellular vesicles; metastatic npc; npc; npc cells ... See more keywords

Niemann-Pick disease type C in the newborn period: a single-center experience

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recommendations! Published in 2017 at "European Journal of Pediatrics"

DOI: 10.1007/s00431-017-3020-y

Abstract: AbstractNiemann-Pick disease type C (NPC) is a neurovisceral lysosomal storage disorder with a great variation in clinical spectrum and age at presentation. Clinical features of 10 NPC patients who presented in the newborn period between… read more here.

Keywords: npc; period; newborn period; pick disease ... See more keywords

miR‐29c regulates resistance to paclitaxel in nasopharyngeal cancer by targeting ITGB1

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recommendations! Published in 2019 at "Experimental Cell Research"

DOI: 10.1016/j.yexcr.2019.02.012

Abstract: &NA; Paclitaxel (Taxol) is an anticancer taxane drug commonly used in the treatment of nasopharyngeal carcinoma (NPC). However, resistance to paclitaxel is a major difficulty in developing an effective therapy against NPC. MicroRNAs (miRNAs) are… read more here.

Keywords: npc; taxol; resistance; resistance paclitaxel ... See more keywords

The immunologic advantage of recurrent nasopharyngeal carcinoma from the viewpoint of Galectin-9/Tim-3-related changes in the tumour microenvironment

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recommendations! Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-10386-y

Abstract: Given salvage treatment for recurrent nasopharyngeal carcinoma (NPC) remains a clinical dilemma, immunotherapy targeting NPC-specific immunosuppression may bring new hope. We analyzed the expression of CD8, CD4, Foxp3 and Tim-3 in lymphocytes, and of Galectin-9… read more here.

Keywords: npc; recurrent npc; expression; recurrent ... See more keywords

miR-26a-5p suppresses nasopharyngeal carcinoma progression by inhibiting PTGS2 expression

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recommendations! Published in 2022 at "Cell Cycle"

DOI: 10.1080/15384101.2022.2030168

Abstract: ABSTRACT Nasopharyngeal carcinoma (NPC) has a low five-year survival rate, and its pathogenesis remains unclear. There is an urgent need to improve our understanding of the genetic regulation of NPC tumorigenesis and development. The role… read more here.

Keywords: nasopharyngeal carcinoma; ptgs2 expression; expression; npc ... See more keywords

Astragaloside IV inhibits nasopharyngeal carcinoma progression by suppressing the SATB2/Wnt signaling axis

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recommendations! Published in 2025 at "Toxicology Research"

DOI: 10.1093/toxres/tfaf047

Abstract: Abstract   Astragaloside IV (AS-IV), a major bioactive component of Astragalus membranaceus, exhibits anti-cancer and anti-inflammatory properties. However, its precise role in nasopharyngeal carcinoma (NPC) remains unclear. This study investigated the effects of AS-IV on… read more here.

Keywords: npc; progression; wnt pathway; nasopharyngeal carcinoma ... See more keywords

TurboID Identification of Evolutionarily Divergent Components of the Nuclear Pore Complex in the Malaria Model Plasmodium berghei

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recommendations! Published in 2022 at "mBio"

DOI: 10.1128/mbio.01815-22

Abstract: The nuclear pore complex (NPC) is a platform for constant evolution and has been used to study the evolutionary patterns of early-branching eukaryotes. The Plasmodium NPC is poorly defined due to its evolutionary divergent nature… read more here.

Keywords: nuclear pore; pore complex; plasmodium; npc ... See more keywords

Septin 9 Methylation in Nasopharyngeal Swabs: A Potential Minimally Invasive Biomarker for the Early Detection of Nasopharyngeal Carcinoma

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recommendations! Published in 2020 at "Disease Markers"

DOI: 10.1155/2020/7253531

Abstract: Nasopharyngeal carcinoma (NPC) is highly prevalent in Southeast Asia, and an unfavorable outcome is usually attributed to advanced stage NPC. Current methods for the early diagnosis of NPC have limitations in clinical practice. The aim… read more here.

Keywords: methylation; npc; septin; detection nasopharyngeal ... See more keywords

Upregulation of PNCK Promotes Metastasis and Angiogenesis via Activating NF-κB/VEGF Pathway in Nasopharyngeal Carcinoma

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recommendations! Published in 2022 at "Journal of Oncology"

DOI: 10.1155/2022/8541582

Abstract: Background Distant metastasis is the major cause of treatment failure in patients with nasopharyngeal carcinoma (NPC). Thus, the identification of the molecular mechanisms and the development of novel therapeutic strategies are important. Previous studies suggest… read more here.

Keywords: metastasis; nasopharyngeal carcinoma; upregulation pnck; pnck ... See more keywords