A perinuclear α-helix with amphipathic features in Brl1 promotes NPC assembly
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e21-12-0616
Abstract: How nuclear pore complexes (NPCs) assemble in the intact nuclear envelope (NE) is only rudimentarily understood. Nucleoporins (Nups) accumulate at the inner nuclear membrane (INM) and deform this membrane toward the outer nuclear membrane (ONM),… read more here.
Keywords: helix amphipathic; amphipathic features; membrane; npc assembly ... See more keywords
An amphipathic helix in Brl1 is required for nuclear pore complex biogenesis in S. cerevisiae
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.78385
Abstract: The nuclear pore complex (NPC) is the central portal for macromolecular exchange between the nucleus and cytoplasm. In all eukaryotes, NPCs assemble into an intact nuclear envelope (NE) during interphase, but the process of NPC… read more here.
Keywords: amphipathic helix; nuclear pore; brl1; biogenesis ... See more keywords