Articles with "npc cells" as a keyword



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EGFR‐rich extracellular vesicles derived from highly metastatic nasopharyngeal carcinoma cells accelerate tumour metastasis through PI3K/AKT pathway‐suppressed ROS

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Published in 2020 at "Journal of Extracellular Vesicles"

DOI: 10.1002/jev2.12003

Abstract: Abstract Nasopharyngeal carcinoma (NPC) is the most common cancer with high metastatic potential that occurs in the epithelial cells of the nasopharynx. Distant metastases are the primary cause for treatment failure and mortality of NPC… read more here.

Keywords: extracellular vesicles; metastatic npc; npc; npc cells ... See more keywords

LINC00324 suppresses apoptosis and autophagy in nasopharyngeal carcinoma through upregulation of PAD4 and activation of the PI3K/AKT signaling pathway.

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Published in 2021 at "Cell biology and toxicology"

DOI: 10.1007/s10565-021-09632-x

Abstract: BACKGROUND Nasopharyngeal carcinoma (NPC) has high incidence in Southern China and is derived from the mucosal epithelium of the nasopharynx. Accumulating evidence has revealed that peptidyl arginine deiminase 4 (PAD4) exerts carcinogenic effect on certain… read more here.

Keywords: pad4; upregulation; pi3k akt; apoptosis autophagy ... See more keywords
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Interferon β and Anti-PD-1/PD-L1 Checkpoint Blockade Cooperate in NK Cell-Mediated Killing of Nasopharyngeal Carcinoma Cells

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Published in 2019 at "Translational Oncology"

DOI: 10.1016/j.tranon.2019.04.017

Abstract: Nasopharyngeal carcinoma (NPC) is a highly malignant epithelial cancer linked to EBV infection. Addition of interferon-β (IFNβ) to chemo- and radiochemotherapy has led to survival rates >90% in children and adolescents. As NPC cells are… read more here.

Keywords: interferon anti; trail; ifn; npc cells ... See more keywords
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Down-regulated long non-coding RNA LHFPL3 antisense RNA 1 inhibits the radiotherapy resistance of nasopharyngeal carcinoma via modulating microRNA-143-5p/homeobox A6 axis.

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Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2021.2024386

Abstract: The function of long non-coding RNA LHFPL3 antisense RNA 1 (LHFPL3-AS1) in cancer progression has been studied, while its role in nasopharyngeal carcinoma (NPC) remains unclear. This study aims to unravel the effects of LHFPL3-AS1… read more here.

Keywords: mir 143; hoxa6; lhfpl3 as1; npc cells ... See more keywords
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3-Bromopyruvate enhances TRAIL-induced apoptosis in human nasopharyngeal carcinoma cells through CHOP-dependent upregulation of TRAIL-R2

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Published in 2017 at "Anti-Cancer Drugs"

DOI: 10.1097/cad.0000000000000502

Abstract: Past reports have shown that the sensitivity of cancer cells to TRAIL-induced apoptosis is related to their expression of TRAIL-death receptors on the cell surface. However, the level of TRAIL-death receptors expression on cancer cells… read more here.

Keywords: trail; induced apoptosis; npc cells; cells trail ... See more keywords
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Effect of GADD45G on the radioresistance of nasopharyngeal carcinoma cells.

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Published in 2021 at "Anti-cancer drugs"

DOI: 10.1097/cad.0000000000001145

Abstract: The development of radioresistance by nasopharyngeal carcinoma (NPC) cells almost always results in tumor recurrence and metastasis, making clinical treatment of the disease difficult. In this study, the mechanism of radioresistance in NPC cells was… read more here.

Keywords: radioresistance; radioresistance nasopharyngeal; npc cells; cell ... See more keywords
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LPLUNC1 reduces glycolysis in nasopharyngeal carcinoma cells through the PHB1‐p53/c‐Myc axis

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Published in 2022 at "Cancer Science"

DOI: 10.1111/cas.15662

Abstract: Cancer cells prefer glycolysis to support their proliferation. Our previous studies have shown that the long palate, lung, and nasal epithelial cell clone 1 (LPLUNC1) can upregulate prohibitin 1 (PHB1) expression to inhibit the proliferation… read more here.

Keywords: expression; lplunc1; glycolysis; p53 ... See more keywords
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Loss of AKR1C1 is a good prognostic factor in advanced NPC cases and increases chemosensitivity to cisplatin in NPC cells

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Published in 2020 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.15291

Abstract: Cisplatin resistance is one of the main obstacles in the treatment of advanced nasopharyngeal carcinoma (NPC). AKR1C1 is a member of the Aldo‐keto reductase superfamily (AKRs), which converts aldehydes and ketones to their corresponding alcohols… read more here.

Keywords: good prognostic; prognostic factor; cisplatin; npc cells ... See more keywords
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LINC01140 Regulates Radiosensitivity of Nasopharyngeal Carcinoma Cells Through the ceRNA Network.

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Published in 2022 at "Cellular and molecular biology"

DOI: 10.14715/cmb/2022.68.4.10

Abstract: Nasopharyngeal carcinoma (NPC) is one of the most lethal head and neck cancers, threatening the health of people across the globe, especially in East and Southeast Asia, the Arctic, the Middle East and North Africa.… read more here.

Keywords: nasopharyngeal carcinoma; radiosensitivity npc; linc01140; radiosensitivity ... See more keywords
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Ginsenoside Rg3 Sensitizes Nasopharyngeal Carcinoma Cells to Radiation by Suppressing Epithelial Mesenchymal Transition

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Published in 2023 at "Radiation Research"

DOI: 10.1667/rade-22-00183.1

Abstract: Radioresistance restrains the therapeutic effect of nasopharyngeal carcinoma (NPC). Ginsenoside Rg3 (Rg3), an active pharmaceutical component extracted from ginseng, shows antitumor effects in various cancers. In this study, we aimed to determine whether Rg3 sensitized… read more here.

Keywords: nasopharyngeal carcinoma; ginsenoside rg3; rg3; radiation ... See more keywords
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RGS17 inhibits tumorigenesis and improves 5-fluorouracil sensitivity in nasopharyngeal carcinoma

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Published in 2018 at "OncoTargets and therapy"

DOI: 10.2147/ott.s176002

Abstract: Background Nasopharyngeal carcinoma (NPC) is a poorly differentiated malignant tumor, and 5-fluorouracil (5-FU) is one of the most effective chemotherapeutic drugs used for the treatment of NPC. Abnormal expression of RGS17 had been shown to… read more here.

Keywords: rgs17; sensitivity; npc cells; nasopharyngeal carcinoma ... See more keywords