Contribution of CTCF binding to transcriptional activity at the HOXA locus in NPM1-mutant AML cells
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DOI: 10.1038/s41375-020-0856-3
Abstract: Transcriptional regulation of the HOXA genes is thought to involve CTCF-mediated chromatin loops and the opposing actions of the COMPASS and Polycomb epigenetic complexes. We investigated the role of these mechanisms at the HOXA cluster… read more here.
Keywords: npm1 mutant; hoxa; ctcf binding; hoxa locus ... See more keywords