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Published in 2017 at "Molecular immunology"
DOI: 10.1016/j.molimm.2017.07.012
Abstract: NPS 2143, a novel and selective antagonist of calcium-sensing receptor (CaSR) has been reported to possess anti-inflammatory activity. In the present study, we examined the protective effect of NPS 2143 on lipopolysaccharide (LPS)-induced acute lung…
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Keywords:
nps;
nps 2143;
antagonist;
sensing receptor ... See more keywords
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Published in 2022 at "Photochemistry and photobiology"
DOI: 10.1111/php.13615
Abstract: The epidermis maintains a cellular calcium gradient, that supports keratinocyte differentiation from its basal layers (low) to outer layers (high) leading to the development of the stratum corneum, which resists penetration of UV radiation. The…
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Keywords:
damage;
damage skin;
nps 2143;
induced dna ... See more keywords
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Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms221810124
Abstract: Pharmacological allosteric agonists (calcimimetics) of the extracellular calcium-sensing receptor (CaSR) have substantial gastro-intestinal side effects and induce the expression of inflammatory markers in colon cancer cells. Here, we compared the effects of both CaSR-specific (R…
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Keywords:
nps 2143;
colon cancer;
casr;
cancer cells ... See more keywords