Loss of NR2E3 represses AHR by LSD1 reprogramming, is associated with poor prognosis in liver cancer
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DOI: 10.1038/s41598-017-11106-2
Abstract: The aryl hydrocarbon receptor (AHR) plays crucial roles in inflammation, metabolic disorder, and cancer. However, the molecular mechanisms regulating AHR expression remain unknown. Here, we found that an orphan nuclear NR2E3 maintains AHR expression, and… read more here.
Keywords: ahr expression; cancer; lsd1; liver cancer ... See more keywords