NR3C1/Glucocorticoid receptor activation promotes pancreatic β-cell autophagy overload in response to glucolipotoxicity.
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DOI: 10.1080/15548627.2023.2200625
Abstract: Diabetes is a complex and heterogeneous disorder characterized by chronic hyperglycemia. Its core cause is progressively impaired insulin secretion by pancreatic β-cell failures, usually upon a background of pre-existing insulin resistance. Recent studies demonstrate that… read more here.
Keywords: cell; glucocorticoid receptor; pancreatic cell; nr3c1 glucocorticoid ... See more keywords