Study of the NR4A family gene expression in patients with multiple sclerosis treated with Fingolimod
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Neurology"
DOI: 10.1111/ene.13875
Abstract: Fingolimod is a drug approved for treatment of relapsing‐remitting multiple sclerosis (RRMS) that exerts its effects via sequestering lymphocytes within the lymph nodes. The drug, acting on the sphingosine‐1‐phosphate pathway, is involved in a plethora… read more here.
Keywords: sclerosis; family gene; nr4a family; gene expression ... See more keywords
Role of the Orphan Nuclear Receptor NR4A Family in T-Cell Biology
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2020.624122
Abstract: The nuclear orphan receptors NR4A1, NR4A2, and NR4A3 are immediate early genes that are induced by various signals. They act as transcription factors and their activity is not regulated by ligand binding and are thus… read more here.
Keywords: nr4a family; biology; role orphan; receptor ... See more keywords