Nuclear receptor 4A1 (NR4A1) antagonists target paraspeckle component 1 (PSPC1) in cancer cells.
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DOI: 10.1002/mc.23362
Abstract: Paraspeckles compound 1 (PSPC1) is a multifunctional protein that plays an important role in cancer cells, where PSPC1 is a master regulator of pro-oncogenic responses that includes activation of TGFβ (TGFβ1), TGFβ-dependent EMT, and metastasis. The… read more here.
Keywords: receptor 4a1; nr4a1 antagonists; nuclear receptor; pspc1 ... See more keywords