A novel lncRNA NR4A1AS upregulates orphan nuclear receptor NR4A1 expression by blocking UPF1-mediated mRNA destabilization in colorectal cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical science"
DOI: 10.1042/cs20181061
Abstract: Long non-coding RNAs (lncRNAs) play important roles in tumorigenesis and cancer progression. The orphan nuclear receptor NR4A1 acts as an oncogene, and is involved in colorectal cancer (CRC) development. However, the mechanism through which lncRNA… read more here.
Keywords: expression; cancer; crc; nr4a1 expression ... See more keywords