Abstract A31: Deregulation of NOTCH 1/NR4A2 signaling axis in head and neck cancer pathogenesis
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DOI: 10.1158/1557-3265.aacrahns19-a31
Abstract: Background: Notch1 and its intracellular cytoplasmic domain (NICD) are dysregulated in many solid tumors, including head and neck squamous cell carcinoma (HNSCC), and associated with disease initiation and progression. NICD-mediated upregulation of nuclear receptor related… read more here.
Keywords: signaling axis; pathogenesis; cancer; nr4a2 signaling ... See more keywords