Analysis of NRAS gain in 657 patients with melanoma and evaluation of its sensitivity to a MEK inhibitor.
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DOI: 10.1016/j.ejca.2017.11.011
Abstract: BACKGROUND Neuroblastoma rat-sarcoma (NRAS) mutations have been described in Chinese patients with melanoma. However, the status and the clinical significance of NRAS gain have not been investigated on a large scale. METHODS A total of… read more here.
Keywords: patients melanoma; nras gain; mek inhibitor;