Somatic NRAS mutation in patient with generalized lymphatic anomaly
Sign Up to like & getrecommendations! Published in 2018 at "Angiogenesis"
DOI: 10.1007/s10456-018-9595-8
Abstract: Generalized lymphatic anomaly (GLA or lymphangiomatosis) is a rare disease characterized by a diffuse proliferation of lymphatic vessels in skin and internal organs. It often leads to progressive respiratory failure and death, but its etiology… read more here.
Keywords: nras mutation; generalized lymphatic; somatic nras; lymphatic anomaly ... See more keywords
Is there any correlation among MKK4 (mitogen-activated protein kinase kinase 4) expression, clinicopathological features, and KRAS/NRAS mutation in colorectal cancer
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DOI: 10.1080/14737159.2020.1784728
Abstract: ABSTRACT Background We aimed to evaluate the correlation between MKK4 expression and clinicopathological features, KRAS/NRAS mutation in colorectal cancer. Methods MKK4 expression was assessed by immunoreactivity score (IRS). Staining intensity(SI) and percentage of positively stained… read more here.
Keywords: nras mutation; kras nras; kinase; correlation ... See more keywords
Association of NRAS Mutation With Clinical Outcomes of Anti-PD-1 Monotherapy in Advanced Melanoma: A Pooled Analysis of Four Asian Clinical Trials
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DOI: 10.3389/fimmu.2021.691032
Abstract: Background Anti-PD-1 monotherapy is the standard therapy for advanced melanoma patients, including those with NRAS mutations. The influence of NRAS mutation on immunotherapy, especially in noncutaneous melanoma, is largely uncharacterized. Materials and Methods We analyzed… read more here.
Keywords: melanoma; advanced melanoma; nras mutation; nras mutations ... See more keywords