Arbutin attenuates ethanol‐induced acute hepatic injury by the modulation of oxidative stress and Nrf‐2/HO‐1 signaling pathway
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22872
Abstract: Alcoholic liver disease (ALD) is a pervasive ailment due to the excessive consumption of alcohol and there is no operative drug for its treatment. The current exploration was intended to examine the hepatoprotective efficacy of… read more here.
Keywords: ethanol provoked; arbutin; nrf signaling; injury ... See more keywords
A novel 2-oxopyrrolidine derivative (LN-53) efficiently induces Nrf-2 signaling pathway activation in human epidermal keratinocytes
Sign Up to like & getrecommendations! Published in 2025 at "Pharmacological Reports"
DOI: 10.1007/s43440-025-00757-y
Abstract: The skin is a pivotal organ that serves as a physical barrier, protecting the body from harmful substances such as pathogens, allergens, and other environmental irritants. Chronic inflammation in the skin, along with the anthropogenic… read more here.
Keywords: activation; human epidermal; epidermal keratinocytes; nrf signaling ... See more keywords
Human Neural Stem Cell Secretome Inhibits Neuron Heme Uptake and Ferroptosis in Intracerebral Hemorrhage through Nrf-2 Signaling Pathway.
Sign Up to like & getrecommendations! Published in 2023 at "Stem cells and development"
DOI: 10.1089/scd.2023.0010
Abstract: Intracerebral hemorrhage (ICH) is a common subtype of stroke with a very high mortality rate, but there is still no effective cure. Increasing evidence suggests that heme accumulation and neuronal ferroptosis play an important role… read more here.
Keywords: nrf signaling; signaling pathway; stem; ferroptosis ... See more keywords
Tangeretin Inhibits Oxidative Stress and Inflammation via Upregulating Nrf-2 Signaling Pathway in Collagen-Induced Arthritic Rats
Sign Up to like & getrecommendations! Published in 2019 at "Pharmacology"
DOI: 10.1159/000501163
Abstract: Background/Aims: Tangeretin (TAN), a major phytochemical in tangerine peels and an important Chinese herb, has multiple biological properties, especially antioxidative and anti-inflammatory effects. However, the mechanisms remain unclear. Based on these findings, the aim of… read more here.
Keywords: oxidative stress; signaling pathway; collagen induced; nrf signaling ... See more keywords