Anti-inflammatory mechanisms of suppressors of cytokine signaling target ROS via NRF-2/thioredoxin induction and inflammasome activation in macrophages
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DOI: 10.5483/bmbrep.2020.53.12.161
Abstract: Suppressors of cytokine signaling (SOCS) exhibit diverse anti-inflammatory effects. Since ROS acts as a critical mediator of inflammation, we have investigated the anti-inflammatory mechanisms of SOCS via ROS regulation in monocytic/macrophagic cells. Using PMA-differentiated monocytic… read more here.
Keywords: nrf thioredoxin; anti inflammatory; inflammatory mechanisms; thioredoxin ... See more keywords