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1
Published in 2022 at "Molecular and Cellular Biology"
DOI: 10.1128/mcb.00563-21
Abstract: Nrf2 activates cytoprotective gene expression, and Nrf2 activity is regulated through at least two protein degradation pathways: the Keap1-mediated and β-TrCP-mediated pathways. To address the relative contributions of these pathways, we generated knock-in mouse lines…
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Keywords:
mediated pathway;
trcp mediated;
keap1 mediated;
nrf2 activity ... See more keywords
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2
Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11091810
Abstract: Acute kidney injury (AKI) is a rapid decline in renal function and can occur after ischemia/reperfusion injury (IRI) to the tubular epithelia. The nuclear factor erythroid-2-related factor 2 (NRF2) pathway protects against AKI and AKI-to-chronic…
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Keywords:
acute kidney;
iri;
activity;
injury ... See more keywords