NRF2 addiction in cancer cells
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Science"
DOI: 10.1111/cas.13537
Abstract: The Kelch‐like ECH‐associated protein 1/nuclear factor erythroid‐derived 2‐like 2 (KEAP1‐NRF2) system is a pivotal defense mechanism against oxidative and electrophilic stress. Although transient NRF2 activation in response to stress is beneficial for health, persistent NRF2… read more here.
Keywords: addicted cancers; nrf2 addicted; cells nrf2; nrf2 addiction ... See more keywords
The KEAP1-NRF2 System and Esophageal Cancer
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DOI: 10.3390/cancers14194702
Abstract: Simple Summary NRF2-activated or NRF2-addicted cancers show high incidence, especially in esophageal squamous cell carcinoma (ESCC). ESCC with high NRF2 expression is largely resistant to the current major treatments for ESCC and therefore shows a… read more here.
Keywords: nrf2 system; system; keap1 nrf2; nrf2 addicted ... See more keywords