Articles with "nrf2 knockout" as a keyword



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The effects of Nrf2 knockout on regulation of benzene‐induced mouse hematotoxicity

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Published in 2018 at "Toxicology and Applied Pharmacology"

DOI: 10.1016/j.taap.2018.09.002

Abstract: ABSTRACT Previous studies have demonstrated that oxidative stress is implicated in benzene‐induced hematotoxicity. However, the low dose‐response effects and the mechanism underlying perturbation of hematopoiesis remain to be defined. This study aims to address the… read more here.

Keywords: benzene induced; benzene; regulation benzene; induced hematotoxicity ... See more keywords
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Nrf2 Knockout Affected the Ferroptosis Signaling Pathway against Cisplatin-Induced Hair Cell-Like HEI-OC1 Cell Death

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Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/2210733

Abstract: Cisplatin is a well-known and widely used anticancer drug with high therapeutic efficacy in solid tumors; however, side effects are common with its use. Because cisplatin can be retained in the cochlea, ototoxicity leading to… read more here.

Keywords: nrf2 knockout; cell; hei oc1; cisplatin induced ... See more keywords