Protective properties of Huperzine A through activation Nrf2/ARE‐mediated transcriptional response in X‐rays radiation‐induced NIH3T3 cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26919
Abstract: Huperzine A (HupA), derived from Huperzia Serrata, has exhibited a variety of biological actions, in particular neuroprotective effect. However, the protective activities of HupA on murine embryonic fibroblast NIH3T3 cells after X‐rays radiation have not… read more here.
Keywords: protective properties; radiation induced; nih3t3 cells; rays radiation ... See more keywords
Danshen modulates Nrf2-mediated signaling pathway in cisplatin-induced renal injury
Sign Up to like & getrecommendations! Published in 2017 at "Current Medical Science"
DOI: 10.1007/s11596-017-1801-1
Abstract: SummaryDanshen, an efficacious agent for cardiovascular diseases, has been found to play an essential role in kidney injury. In the present study, the effect of Danshen on cisplatin-induced renal dysfunction was investigated in a mouse… read more here.
Keywords: cisplatin; danshen; nrf2 mediated; induced renal ... See more keywords
Anthraquinone and naphthopyrone glycosides from Cassia obtusifolia seeds mediate hepatoprotection via Nrf2-mediated HO-1 activation and MAPK modulation
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Pharmacal Research"
DOI: 10.1007/s12272-018-1040-4
Abstract: Cassia obtusifolia L. seed is one of the most popular traditional Chinese medicine for mutagenicity, genotoxicity, hepatotoxicity, and acute inflammatory diseases. We evaluated the hepatoprotective activity of anthraquinone and naphthopyrone glycosides isolated from the butanol… read more here.
Keywords: anthraquinone naphthopyrone; naphthopyrone glycosides; nrf2 mediated; via nrf2 ... See more keywords
Polydatin attenuates reactive oxygen species‐induced airway remodeling by promoting Nrf2‐mediated antioxidant signaling in asthma mouse model
Sign Up to like & getrecommendations! Published in 2019 at "Life Sciences"
DOI: 10.1016/j.lfs.2018.08.013
Abstract: ABSTRACT Reactive oxygen species (ROS) and epithelial–mesenchymal transition (EMT) play a critical role in transforming growth factor (TGF)‐&bgr;1‐mediated fibrotic airway remodeling in asthma. Polydatin (PD) is a small natural molecule in Chinese medicine; it is… read more here.
Keywords: nrf2 mediated; tgf bgr; model; promoting nrf2 ... See more keywords
DNA Microarray Profiling Highlights Nrf2-Mediated Chemoprevention Targeted by Wasabi-Derived Isothiocyanates in HepG2 Cells
Sign Up to like & getrecommendations! Published in 2017 at "Nutrition and Cancer"
DOI: 10.1080/01635581.2017.1248296
Abstract: ABSTRACT 6-MSITC and 6-MTITC are sulforaphane (SFN) analogs found in Japanese Wasabi. As we reported previously, Wasabi isothiocyanates (ITCs) are activators of Nrf2-antioxidant response element pathway, and also inhibitors of pro-inflammatory cyclooxygenase-2. This study is… read more here.
Keywords: wasabi; nrf2 mediated; hepg2 cells; dna microarray ... See more keywords
Nrf2-Mediated HO-1 Induction and Antineuroinflammatory Activities of Halleridone.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of medicinal food"
DOI: 10.1089/jmf.2017.3949
Abstract: Nuclear factor E2-related factor 2 (Nrf2) is the master regulator of antioxidant enzymes and is known to act on the nuclear factor kappa-light-chain-enhancer of activated B cell (NF-κB) signaling pathway. Few studies have examined the… read more here.
Keywords: induction antineuroinflammatory; nrf2 mediated; antineuroinflammatory activities; expression ... See more keywords
Antifatigue effects of anshenyizhi compound in acute excise-treated mouse via modulation of AMPK/PGC-1α-related energy metabolism and Nrf2/ARE-mediated oxidative stress.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of food science"
DOI: 10.1111/1750-3841.15149
Abstract: The anshenyizhi compound (AC), a mixture from Chinese medicine herbs, has numerous biological effects. In the present study, the acute exercise-treated mice model was established to explore the antifatigue properties of AC and its underlying… read more here.
Keywords: mediated oxidative; metabolism; nrf2 mediated; anshenyizhi compound ... See more keywords
Influenza A Virus Uses PSMA2 for Downregulation of the NRF2-Mediated Oxidative Stress Response
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.01990-21
Abstract: Influenza A virus (IAV) remains one of the most significant infectious agents, responsible for 3 million to 5 million illnesses each year and more than 50 million deaths during the 20th century. The cellular processes… read more here.
Keywords: psma2; iav infection; influenza virus; nrf2 mediated ... See more keywords
Nrf2-mediated anti-inflammatory polarization of macrophages as therapeutic targets for osteoarthritis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.967193
Abstract: Macrophages are the most abundant immune cells within the synovial joints, and also the main innate immune effector cells triggering the initial inflammatory responses in the pathological process of osteoarthritis (OA). The transition of synovial… read more here.
Keywords: mediated anti; signaling pathway; inflammatory polarization; anti inflammatory ... See more keywords
Infectious spleen and kidney necrosis virus induces the reactive oxidative species/Nrf2-mediated oxidative stress response for the regulation of mitochondrion-mediated Bax/Bak cell death signals in GF-1 cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.958476
Abstract: Infectious spleen and kidney necrosis virus (ISKNV) infections can trigger host cell death and are correlated with viral replication; however, they have rarely been considered in terms of the host organelle involvement. In the present… read more here.
Keywords: cell death; bax bak; stress; oxidative stress ... See more keywords
Autophagy Controls Nrf2-Mediated Dichotomy in Pressure Overloaded Hearts
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.673145
Abstract: Burgeoning evidence has indicated that normal autophagy is required for nuclear factor erythroid 2-related factor (Nrf2)-mediated cardiac protection whereas autophagy inhibition turns on Nrf2-mediated myocardial damage and dysfunction in a setting of pressure overload (PO).… read more here.
Keywords: autophagy inhibition; nrf2 mediated; autophagy; autophagy controls ... See more keywords