Articles with "nrf2 mrp2" as a keyword



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Tanshinone IIA prevents acetaminophen‐induced nephrotoxicity through the activation of the Nrf2‐Mrp2/4 pathway in mice

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Published in 2022 at "Environmental Toxicology"

DOI: 10.1002/tox.23511

Abstract: It's known that APAP overdose often leads to hepatotoxicity and nephrotoxicity. In the present study, we investigated the preventative effect of Tan IIA on APAP‐induced nephrotoxicity. Mice were orally administrated with Tan IIA (10 or… read more here.

Keywords: nrf2 mrp2; iia; tan iia; mice ... See more keywords