2‐undecanone protects against fine particles‐induced heart inflammation via modulating Nrf2/HO‐1 and NF‐κB pathways
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23513
Abstract: Exposure to air pollution has been closely associated with some cardiovascular disease. One of the mechanisms of PM2.5‐mediated heart injury may be to promote inflammation. We aim to investigate whether the main extract of Houttuynia… read more here.
Keywords: inflammation; nrf2 pathways; heart; pm2 ... See more keywords
Dl-3-n-Butylphthalide improves lipopolysaccharide-induced depressive-like behavior in rats: involvement of Nrf2 and NF-κB pathways
Sign Up to like & getrecommendations! Published in 2018 at "Psychopharmacology"
DOI: 10.1007/s00213-018-4949-x
Abstract: Rationale and objectivesDl-3-n-Butylphthalide (NBP), a small molecule compound extracted from the seeds of Apium graveolens, possesses a large range of biological effects. Here, we attempted to explore the therapeutic effects of NBP on lipopolysaccharide (LPS)-induced… read more here.
Keywords: lps induced; apoptosis; butylphthalide improves; depressive like ... See more keywords
Ginsenoside Rg1 protects mice against streptozotocin-induced type 1 diabetic by modulating the NLRP3 and Keap1/Nrf2/HO-1 pathways.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.172801
Abstract: Ginseng has been traditionally used to treat diabetes mellitus (DM) in China. Ginsenoside Rg1 is a major active ingredient in processed ginseng, which elicits proven biological and pharmacological effects. Although a correlation between nucleotide-binding oligomerization… read more here.
Keywords: ginsenoside rg1; keap1 nrf2; rg1 protects; nlrp3 keap1 ... See more keywords
Suppression of endoplasmic reticulum stress-dependent autophagy enhances cynaropicrin-induced apoptosis via attenuation of the P62/Keap1/Nrf2 pathways in neuroblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.977622
Abstract: Autophagy has dual roles in cancer, resulting in cellular adaptation to promote either cell survival or cell death. Modulating autophagy can enhance the cytotoxicity of many chemotherapeutic and targeted drugs and is increasingly considered to… read more here.
Keywords: apoptosis; keap1 nrf2; p62 keap1; nrf2 pathways ... See more keywords
Consumption of Anacardium occidentale L. (Cashew Nuts) Inhibits Oxidative Stress through Modulation of the Nrf2/HO−1 and NF-kB Pathways
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25194426
Abstract: Ischemia/reperfusion injury is a severe disorder associated with a high mortality. Several antioxidant and pharmacological properties of cashew nuts (Anacardium occidentale L.) and its metabolites from different countries have recently been described. It is a… read more here.
Keywords: cashew nuts; reperfusion; nrf2 pathways; anacardium occidentale ... See more keywords