Articles with "nrf2 regulation" as a keyword



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The Intricacies of NRF2 Regulation in Cancer.

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Published in 2021 at "Seminars in cancer biology"

DOI: 10.1016/j.semcancer.2021.05.016

Abstract: The complex role of NRF2 in the context of cancer continues to evolve. As a transcription factor, NRF2 regulates various genes involved in redox homeostasis, protein degradation, DNA repair, and xenobiotic metabolism. As such, NRF2… read more here.

Keywords: protein; nrf2 regulation; intricacies nrf2; cancer ... See more keywords
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Nrf2 Regulation by Curcumin: Molecular Aspects for Therapeutic Prospects

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Published in 2021 at "Molecules"

DOI: 10.3390/molecules27010167

Abstract: Nuclear factor erythroid 2 p45-related factor (2Nrf2) is an essential leucine zipper protein (bZIP) that is primarily located in the cytoplasm under physiological conditions. Nrf2 principally modulates endogenous defense in response to oxidative stress in… read more here.

Keywords: response; nrf2 regulation; protein; regulation ... See more keywords