NRG1-Fc improves metabolic health via dual hepatic and central action.
Sign Up to like & getrecommendations! Published in 2018 at "JCI insight"
DOI: 10.1172/jci.insight.98522
Abstract: Neuregulins (NRGs) are emerging as an important family of signaling ligands that regulate glucose and lipid homeostasis. NRG1 lowers blood glucose levels in obese mice, whereas the brown fat-enriched secreted factor NRG4 protects mice from… read more here.
Keywords: nrg1; action nrg1; metabolic health; nrg1 improves ... See more keywords
Neuregulin1 acts as a suppressor in human lung adenocarcinoma via AKT and ERK1/2 pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of thoracic disease"
DOI: 10.21037/jtd.2018.05.175
Abstract: Background Neuregulin1 (NRG1) is critical signaling protein that mediates the activation of downstream signaling pathways associated with malignancies. Multiple gene fusions related to NRG1 have been found in lung cancer. However, the underlying role NRG1… read more here.
Keywords: lung adenocarcinoma; akt erk1; nrg1; human lung ... See more keywords
Impaired Expression of Neuregulin 1 and Nicotinic Acetylcholine Receptor β4 Subunit in Diverticular Disease
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2019.00563
Abstract: Neuregulin 1 (NRG1) regulates the expression of the nicotinic acetylcholine receptor (nAChR) and is suggested to promote the survival and maintenance of the enteric nervous system (ENS), since deficiency of its corresponding receptor complex ErbB2/ErbB3… read more here.
Keywords: nachr subunit; nrg1; erbb3; expression ... See more keywords