Extreme Glycemic Fluctuations Debilitate NRG1, ErbB Receptors and Olig1 Function: Association with Regeneration, Cognition and Mood Alterations During Diabetes.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular neurobiology"
DOI: 10.1007/s12035-021-02455-1
Abstract: Neuronal regeneration is crucial for maintaining intact neural interactions for perpetuation of cognitive and emotional functioning. The NRG1-ErbB receptor signaling is a key pathway for regeneration in adult brain and also associated with learning and… read more here.
Keywords: nrg1 erbb; erbb receptor; regeneration; extreme glycemic ... See more keywords
NRG1/ErbB signalling controls the dialogue between macrophages and neural crest-derived cells during zebrafish fin regeneration
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-26422-5
Abstract: Fish species, such as zebrafish (Danio rerio), can regenerate their appendages after amputation through the formation of a heterogeneous cellular structure named blastema. Here, by combining live imaging of triple transgenic zebrafish embryos and single-cell… read more here.
Keywords: nrg1 erbb; zebrafish fin; fin regeneration; neural crest ... See more keywords
NRG1-ErbB Lost in Translation: A New Paradigm for Lung Cancer?
Sign Up to like & getrecommendations! Published in 2017 at "Current medicinal chemistry"
DOI: 10.2174/0929867324666170911170554
Abstract: BACKGROUND Molecular lesions of the NRG1 gene were recently described as a new molecular feature of Invasive Mucinous Adenocarcinoma of the lung. The NRG1 chimeric ligand leads to aberrant activation of the ErbB2/ErbB3 signaling via… read more here.
Keywords: nrg1 erbb; lung; lung cancer;
Cartilage regeneration in zebrafish depends on Nrg1/ErbB signaling pathway
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1123299
Abstract: Objective: Cartilage, as the majority of adult mammalian tissues, has limited regeneration capacity. Cartilage degradation consecutive to joint injury or aging then leads to irreversible joint damage and diseases. In contrast, several vertebrate species such… read more here.
Keywords: regeneration; nrg1 erbb; capacity; cartilage ... See more keywords
Astraglaus polysaccharide protects diabetic cardiomyopathy by activating NRG1/ErbB pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Bioscience trends"
DOI: 10.5582/bst.2018.01027
Abstract: Diabetic cardiomyopathy (DCM) is one of the main cardiac complications among diabetic patients. According to previous studies, the pathogenesis of DCM is associated with oxidative stress, apoptosis and proliferation of local cardiac cells. It showed,… read more here.
Keywords: nrg1 erbb; dcm; erbb pathway; astraglaus polysaccharide ... See more keywords